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An examination using murine models of coronary artery tying appeared to exhibit results which implied that TB-500 might elevate integrin-associated kinase (ILK) and protein kinase B operations in the heart, possibly boosting early cardiomyocyte endurance and seemingly enhancing heart performance

TB-500 activates early-phase repair signals: Akt-mediated cell survival, actin-driven cell migration, and MMP-mediated matrix remodeling to clear debris

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